For testing, I'm going to use my Western Digital Caviar 250GB storage drive. Installation for the drive is similar to a normal installation in a case, using the screw holes on the side of the drive to fix the drive in place. The flat top of the hard drive goes up against the cooler for maximum contact. If you think about it, it couldn't be any other way because you might short out the logic board against the cooler.
Once the hard drive is in, you have to attach the vibration dampening thumbscrews. There are two different holes for the thumbscrews—my guess is to account for variation in case designs. The grounding cable can be attached under any one of those thumbscrews, keeping your hard drive safe from Murphy and his crazy laws. Next you can adjust the tension screws to keep an even pressure on your hard drive and make sure that you're not crushing its casing.
Finally, you can just screw the cooler into your case. Cases vary greatly in their mounting designs, and it was particularly hard for me to get mine to sit correctly in my NZXT Apollo because it doesn't have many supporting rails for the 5.25” bays. It would have been nice to see Ultra try to play towards the toolless systems that are being more widely used in cases these days, because those attach to the center screw holes on CD/DVD drives rather than the far wide ones. Nevertheless, installation was quick and painless.