Installing a mATX motherboard in this case was pretty straight forward. All of the standoffs came pre-installed to fit a mATX motherboard. In order to access the back plane where the motherboard will be mounted, the DVD ROM bay will need to be removed which involves removing some screws. You will also want to go ahead and install the power supply (the case does not come with one) as well as the internal hard drive(s) as accessing these areas will be difficult once the motherboard is installed.
The motherboard installed easily, but cabling was quite challenging due to the limited space. It you are the anal-retentive type about neat cabling, this case may present a challenge to you, but it is as to be expected with the relatively small footprint of the case combined with the amount of hardware that can be packed inside of it. The case also doesn't really have any cable management options to speak of aside from a few cable ties so this further aggravates the matter.
All things considered, it is hard to give this case a negative mark for this reason alone, but it is worth mentioning especially if you are a fan of sexy cabling. Also worth noting on this subject: in future iterations, SilverStone should limit the length of the front panel cables as they were longer than they really needed to be and only complicated the wire management situation.
To wrap up the hardware installation, there are a lot of places to put drives and the mATX motherboard fit in quite easily, but don't expect a beautiful cabling job without some hardcore modding. Considering this is a HTPC case, this should come as no surprise.