The P6X58D-E is a variant of the P6X58D Premium offering. The Premium model is $50 more expensive, which nets you an additional LAN port, an onboard reset button, a USB / eSATA expansion bracket, an optional cooling fan and a slightly different chipset cooling setup. If you can do without these few extras (as I suspect most can), save yourself the extra dough as the two boards are otherwise identical.
Starting our tour at the bottom of the board, we find three PCIe 2.0 x16 ports operating in x16/x8/x8 or x16/x16/x1 mode. A PCIe x1 slot flanks the upper PCIe x16 slot at the top with two regular PCI slots spaced between the other two x16 slots. Each of the three PCIe slots feature ASUS' Q-Slot locking technology that makes installing and removing cards easier than traditional methods.
There is a single 3-pin fan connector just to the left of the heatpipe-cooled chipset.
Along the bottom of the board we find, from left to right: front panel audio connector, optical drive audio connector, S/PDIF Out, power button, 1394 FireWire connector, two USB connectors, two SATA connectors and the system panel connectors.
Those who don't care for tiny front panel connectors can use the included Q-Connector to ease installation.
The two blue jumpers above the front panel connectors allow you to increase the available voltage to the DRAM and QPI for extreme overclocking. Unless you are using some heavy-duty watercooling or something more, odds are you won't need to mess with these. But, it's nice that the features are there should you want to venture into the extreme.
More just ahead.