Logitech has done a wonderful job with the software included with the Harmony 720. Pop in the installation/software disc and the Harmony software loads automatically. We are presented with a setup overview which gives us an idea of what to expect from the software. You are required to register with Logitech's online database which will give you access to their extensive library of over 4,200 manufacturers and over 150,000 IR devices. Once you have created your Logitech account, you are then prompted to connect the remote to your computer using the supplied USB cable. The USB cable connects to the front of the remote by removing a rubber plug. Once the connection has been established, you can then begin to add your devices. All you need is the device's manufacturer and model number. I had no issues when searching for my components (TV, Audio Receiver and DVD player).