The micro-ATX board I'm installing is an older 6100 based, socket 754 chipset, which with its single channel memory is not quite as wide as a "full-sized" micro-ATX motherboard, therefore some of the standoffs go unused at the front. As you can see, there is still plenty of room around the perimeter of the board, although things may get a bit tight in the bottom front corner near the hard drive cage. The front panel cables easily reach the motherboard pins, which are usually found along the top edge.
All the drives install painlessly and routing cables isn't too bad either. I mounted a pair of 80mm fans at the rear to assist with exhaust duties. Hopefully they will help to pull some air in over the hard drive through the vented opening in the front panel. Although I'm using the onboard graphics, there is a good deal of space for an add-in video card, even a high-end model. Apevia claims the X-QBOII is 8800GTX compatible, although whether you have to give up the floppy bay cage (which is removable) is unclear. Even so, it's nice to have that option. Obviously you'll need a beefier power supply if this is something in your plans, however since it uses a standard ATX format, finding a replacement shouldn't be a problem.
Let's wrap things up with some final thoughts on the X-QBOII.